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Breakpoints applied in this study <xref ref-type= a " width="250" height="auto" />
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Image Search Results


Survival log-rank (Mantel–Cox) test

Journal: Antimicrobial Agents and Chemotherapy

Article Title: Evaluation of a potent LpxC inhibitor for post-exposure prophylaxis treatment of antibiotic-resistant Burkholderia pseudomallei in a murine infection model

doi: 10.1128/aac.01295-24

Figure Lengend Snippet: Survival log-rank (Mantel–Cox) test

Article Snippet: Antibiotic susceptibility determinations from stock strains yielded ceftazidime MIC of 2 μg/mL and an LPC-233 MIC 90 of 0.03 μg/mL, as determined by the standard Clinical and Laboratory Standards Institute (CLSI) broth microdilution assay ( ).

Techniques:

Breakpoints applied in this study <xref ref-type= a " width="100%" height="100%">

Journal: Journal of Clinical Microbiology

Article Title: Evaluation of antimicrobial susceptibility testing methods for Burkholderia cepacia complex isolates from people with and without cystic fibrosis

doi: 10.1128/jcm.01480-24

Figure Lengend Snippet: Breakpoints applied in this study a

Article Snippet: As of this writing, the Clinical and Laboratory Standards Institute (CLSI) has published minimal inhibitory concentration (MIC) breakpoints for ceftazidime (CAZ), meropenem (MEM), minocycline (MIN), levofloxacin (LVX), trimethoprim-sulfamethoxazole (TMP-SMX), chloramphenicol (CAM), and ticarcillin-clavulanate (TIC) , with CAM being rarely clinically used and TIC not available in the USA.

Techniques:

MIC distribution for BCC isolates tested against CAZ, LVX, MEM, MIN, and TMP-SMX as determined by BMD. Black dashed lines indicate BCC breakpoints from CLSI M100 ED33:2023. Black = CF isolates ( n = 98) and gray = non-CF isolates ( n = 105). #, number.

Journal: Journal of Clinical Microbiology

Article Title: Evaluation of antimicrobial susceptibility testing methods for Burkholderia cepacia complex isolates from people with and without cystic fibrosis

doi: 10.1128/jcm.01480-24

Figure Lengend Snippet: MIC distribution for BCC isolates tested against CAZ, LVX, MEM, MIN, and TMP-SMX as determined by BMD. Black dashed lines indicate BCC breakpoints from CLSI M100 ED33:2023. Black = CF isolates ( n = 98) and gray = non-CF isolates ( n = 105). #, number.

Article Snippet: As of this writing, the Clinical and Laboratory Standards Institute (CLSI) has published minimal inhibitory concentration (MIC) breakpoints for ceftazidime (CAZ), meropenem (MEM), minocycline (MIN), levofloxacin (LVX), trimethoprim-sulfamethoxazole (TMP-SMX), chloramphenicol (CAM), and ticarcillin-clavulanate (TIC) , with CAM being rarely clinically used and TIC not available in the USA.

Techniques:

Scattergrams comparing DD on three different MHA brands to BMD for CAZ, LVX, MEM, MIN, and TMP-SMX, all BCC isolates. Scattergrams were generated by comparing the mode or median BMD MIC (y-axis) to DD zone diameter (x-axis) as measured on Remel, HD, or BD MHA. Solid lines within each scattergram indicate the breakpoints applied. Red, VME; orange, ME; and yellow, MI.

Journal: Journal of Clinical Microbiology

Article Title: Evaluation of antimicrobial susceptibility testing methods for Burkholderia cepacia complex isolates from people with and without cystic fibrosis

doi: 10.1128/jcm.01480-24

Figure Lengend Snippet: Scattergrams comparing DD on three different MHA brands to BMD for CAZ, LVX, MEM, MIN, and TMP-SMX, all BCC isolates. Scattergrams were generated by comparing the mode or median BMD MIC (y-axis) to DD zone diameter (x-axis) as measured on Remel, HD, or BD MHA. Solid lines within each scattergram indicate the breakpoints applied. Red, VME; orange, ME; and yellow, MI.

Article Snippet: As of this writing, the Clinical and Laboratory Standards Institute (CLSI) has published minimal inhibitory concentration (MIC) breakpoints for ceftazidime (CAZ), meropenem (MEM), minocycline (MIN), levofloxacin (LVX), trimethoprim-sulfamethoxazole (TMP-SMX), chloramphenicol (CAM), and ticarcillin-clavulanate (TIC) , with CAM being rarely clinically used and TIC not available in the USA.

Techniques: Generated

Scattergrams comparing DD on three different MHA brands to BMD for CAZ, LVX, MEM, MIN, and TMP-SMX, CF isolates. Scattergrams were generated by comparing the mode or median BMD MIC (y-axis) to DD zone diameter (x-axis) as measured on Remel, HD, or BD MHA for CF isolates. Solid lines within each scattergram indicate the breakpoints applied. Red, VME; orange, ME; and yellow, MI.

Journal: Journal of Clinical Microbiology

Article Title: Evaluation of antimicrobial susceptibility testing methods for Burkholderia cepacia complex isolates from people with and without cystic fibrosis

doi: 10.1128/jcm.01480-24

Figure Lengend Snippet: Scattergrams comparing DD on three different MHA brands to BMD for CAZ, LVX, MEM, MIN, and TMP-SMX, CF isolates. Scattergrams were generated by comparing the mode or median BMD MIC (y-axis) to DD zone diameter (x-axis) as measured on Remel, HD, or BD MHA for CF isolates. Solid lines within each scattergram indicate the breakpoints applied. Red, VME; orange, ME; and yellow, MI.

Article Snippet: As of this writing, the Clinical and Laboratory Standards Institute (CLSI) has published minimal inhibitory concentration (MIC) breakpoints for ceftazidime (CAZ), meropenem (MEM), minocycline (MIN), levofloxacin (LVX), trimethoprim-sulfamethoxazole (TMP-SMX), chloramphenicol (CAM), and ticarcillin-clavulanate (TIC) , with CAM being rarely clinically used and TIC not available in the USA.

Techniques: Generated

Scattergrams DD on three different MHA brands to BMD for CAZ, LVX, MEM, MIN, and TMP-SMX, non-CF isolates. Scattergrams were generated by comparing the mode or median BMD MIC (y-axis) to DD zone diameter (x-axis) as measured on Remel, HD, or BD MHA for non-CF isolates. Solid lines within each scattergram indicate the breakpoints applied. Red, VME; orange, ME; and yellow, MI.

Journal: Journal of Clinical Microbiology

Article Title: Evaluation of antimicrobial susceptibility testing methods for Burkholderia cepacia complex isolates from people with and without cystic fibrosis

doi: 10.1128/jcm.01480-24

Figure Lengend Snippet: Scattergrams DD on three different MHA brands to BMD for CAZ, LVX, MEM, MIN, and TMP-SMX, non-CF isolates. Scattergrams were generated by comparing the mode or median BMD MIC (y-axis) to DD zone diameter (x-axis) as measured on Remel, HD, or BD MHA for non-CF isolates. Solid lines within each scattergram indicate the breakpoints applied. Red, VME; orange, ME; and yellow, MI.

Article Snippet: As of this writing, the Clinical and Laboratory Standards Institute (CLSI) has published minimal inhibitory concentration (MIC) breakpoints for ceftazidime (CAZ), meropenem (MEM), minocycline (MIN), levofloxacin (LVX), trimethoprim-sulfamethoxazole (TMP-SMX), chloramphenicol (CAM), and ticarcillin-clavulanate (TIC) , with CAM being rarely clinically used and TIC not available in the USA.

Techniques: Generated

Scattergrams comparing AD (left) and ETEST (right) to BMD for CAZ, LVX, MEM, MIN, and TMP-SMX, all BCC isolates. Scattergrams were generated by comparing the composite BMD MIC (y-axis) to AD or ETEST MIC (x-axis). Solid lines within each scattergram indicate the breakpoints applied. Red, VME; orange, ME; and yellow, MI.

Journal: Journal of Clinical Microbiology

Article Title: Evaluation of antimicrobial susceptibility testing methods for Burkholderia cepacia complex isolates from people with and without cystic fibrosis

doi: 10.1128/jcm.01480-24

Figure Lengend Snippet: Scattergrams comparing AD (left) and ETEST (right) to BMD for CAZ, LVX, MEM, MIN, and TMP-SMX, all BCC isolates. Scattergrams were generated by comparing the composite BMD MIC (y-axis) to AD or ETEST MIC (x-axis). Solid lines within each scattergram indicate the breakpoints applied. Red, VME; orange, ME; and yellow, MI.

Article Snippet: As of this writing, the Clinical and Laboratory Standards Institute (CLSI) has published minimal inhibitory concentration (MIC) breakpoints for ceftazidime (CAZ), meropenem (MEM), minocycline (MIN), levofloxacin (LVX), trimethoprim-sulfamethoxazole (TMP-SMX), chloramphenicol (CAM), and ticarcillin-clavulanate (TIC) , with CAM being rarely clinically used and TIC not available in the USA.

Techniques: Generated